有人作过肠道c-kit，SCF免疫组化吗？
CD117 (c-kit) antibody
Clone: YB5.B8
Format: Purified
Isotype: Mouse IgG1, k
W.S. No: V C009
Target Species: Human
Cross Reactivity: Rabbit,Dog
Applications:
Flow Cytometry Recommended APC
Flow Cytometry Recommended PE
Flow Cytometry Recommended Purified, R-PE, PE-Cy5 (BD Cy-Chrome™)
Description
Recognizes CD117 (c-kit), a 145 kDa cell-surface glycoprotein with tyrosine kinase activity. CD117 is present on hematopoietic progenitor cell subsets, tissue mast cells, and melanocytes. CD117 serves as a cytokine receptor for steel factor (SLF), also known as stem cell factor (SCF) or mast cell growth factor (MGF). The interaction of c-kit and SLF is crucial to hematopoiesis, mast cell differentiation, melanogenesis, and germ cell development. The ability of YB5.B8 antibody to block the binding of c-kit ligand is still controversial.
This antibody is suitable for staining acetone-fixed, frozen tissue sections.
